About the position

A 2-year Postdoctoral fellow/Researcher position is available in the “Autophagy in Cancer” Team headed by Dr. Nikolai Engedal at the Department of Tumor Biology (www.ous-research.no/engedal).

We are seeking an ambitious, curious and dedicated scientist and team player with strong interests in autophagy, metabolism, and tumor cell biology.

The position is part of a project called “AUTOcope”, which is funded by the South-Eastern Norway Regional Health Authority. The project aims to understand the role of autophagy in the crosstalk between cancer cells and cancer-associated fibroblasts (CAFs), with a particular focus on metabolic rewiring and cellular coping with tumor microenvironment stress. A summary of the project can be found here: https://forskningsprosjekter.ihelse.net/prosjekt/2024072.

The postdoctoral fellow/researcher will work in collaboration with team participants within the group, core facilities, and external project partners.

Oslo University Hospital is the largest hospital in Scandinavia, and the Institute for Cancer Research the largest cancer research environment in Norway. A short presentation of the Institute can be viewed here (youtu.be/MtcgDwqB_6Q). 

Kvalifikasjoner:

• PhD degree in experimental cellular and molecular biology, or similar 
• A strong and relevant track record 
• Knowledge and experience with cell culture, cell-based assays, and standard molecular cell biology techniques is essential
• Knowledge and experience in metabolism, metabolic analyses, and metabolomics is highly and most desirable
• Knowledge and experience in autophagy research is highly desirable
• Knowledge and experience in bioinformatics, especially within metabolomics and transcriptomics, is highly desirable
• Knowhow in molecular cloning, and experience in producing inducible shRNA vectors, lentiviral vectors and lentivirus is desirable
• Experience in working with co-culture models (in 2D and 3D) is a plus
• Previous experience in working with live tissue and enzymatic tissue digestion is a plus
• Experience in mouse work and/or working with xenograft tissue is a plus
• Experience and skills in supervision and teamwork is an advantage 
• Excellent written and verbal communication in English is required

Personlige egenskaper:

• Able and eager to work independently and in a team
• Scientifically curious and proactive, with drive and commitment to the project
• Self-motivated
• Collaboration-oriented and able to interact with project partners from different fields, including potential research stays in a project partner lab
• Well-organized and methodical
• Excellent communication skills both verbal and written
  

Vi tilbyr:

• A full-time two-year position with the possibility of an extension
• An ambitious and exciting research project in a stimulating scientific environment with excellent opportunities for academic development
• Excellence on prostate cancer research and autophagy within the group, the Department, and neighboring Departments at the Institute.
• Our group is part of the Autophagy Research Centre Targeting Cancer (ARCTIC) https://arctic-autophagy.no/groups/
• Modern locations with cutting-edge technologies and highly competent core facilities, including for flow cytometry and sequencing
• Close proximity to the hospital pathology unit that routinely performs prostate tissue biobanking, paraffin embedding, and immunohistochemistry
• A strong collaborative network
• Competitive salary according to qualifications and the guidelines from the Oslo University Hospital
• Favorable pension arrangements
• Attractive welfare arrangements, with affordable high-quality childcare available

 

How to apply

The application should be written in English and must include:

• Application letter (1-2 page summary of scientific work and motivation for the position and the project)
• CV (summarizing formal education and obtained degrees, positions, academic work, and other relevant activities, skills, and qualities)
• List of publications (submitted manuscripts, including on bioRxiv, may be included)
• Copies of educational certificates with grades
• Letter(s) of recommendation (optional)
• List of 2-3 reference persons (e.g. former coworkers and supervisors, stating their name, position, relation to the candidate, e-mail, and phone number)

 

Interviews with the best qualified candidates will be arranged.

An alternative starting date can be discussed. This position is with the possibility of an extension.